Postdoctoral Research Associate

About the Role

The Solecki Lab is developing imaging-based biosensor platforms to visualize chromatin states and cell polarity decisions in living neurons. We seek postdoctoral fellows interested in building the experimental framework for understanding cell biological transitions during neuronal maturation and brain circuit assembly.

Key Responsibilities

• Carry out independent research projects.
• Utilize live-cell biosensors, advanced microscopy, neuronal differentiation systems, acute perturbations, and quantitative image analysis to investigate intracellular state transitions in developing neurons.
• Contribute to the development of new experimental approaches, including probes, assays, imaging strategies, and perturbation methods.
• Define major research projects within the lab's focus on neuronal maturation, chromatin-state dynamics, polarity transitions, nuclear organization, and circuit assembly.
• Collaborate with the PI and an interdisciplinary team to develop high-risk, high-reward experiments.
• Generate first-author publications.
• Present research at national and international meetings.
• Build a scientific identity at the intersection of developmental neurobiology, live-cell imaging, biosensor engineering, and quantitative cell biology.

Requirements & Tech Stack

• Experience with live-cell imaging.
• Experience with super-resolution microscopy.
• Experience with imaging probe development.
• Familiarity with programming languages for data analysis (e.g., R, Python).
• Exposure to cutting-edge imaging technologies (e.g., lattice light sheet, super-resolution platforms).
• Exposure to data science core labs.

Qualifications

• A PhD in cell biology, biophysics, gene regulation, neuroscience, or a related discipline.
• A strong record of peer-reviewed publications.
• Ability to independently design and execute experiments and interpret data.
• Ability for cogent experimental preparation, validation, documentation, and troubleshooting.

To apply, send a C.V., Description of Research Interests, Outline of Career Aspirations, and contact information for 3 referees to [email protected].