Histology Technician/Histotechnologist

Cleveland Clinic

About the Role

Join Cleveland Clinic’s Main Campus as a Histology Technician/Histotechnologist. This role plays a vital part in preparing high-quality tissue samples to support accurate diagnoses and treatment decisions. You will work as part of a collaborative team dedicated to excellence, directly impacting patient outcomes.

This position is eligible for a sign-on bonus of $5,000.

The caregiver works full-time, with a 3:00 am or 9:30 am start.

Histology Technician Role

  • Prepare, process, embed, and section tissue specimens using standard histology equipment, including microtomes and cryostats.
  • Perform routine and specialized staining procedures, including histochemical and enzyme stains.
  • Mount, label, and distribute slides for pathologist review.
  • Maintain laboratory equipment, perform daily maintenance, and coordinate repairs.
  • Prepare reagents, buffers, and solutions.
  • Accurately document patient and specimen data, maintain records, and track lab statistics.
  • Ensure cleanliness, organization, and quality control of lab instruments and workspaces.
  • Support training and serve as a resource for students, trainees, and residents.

Histotechnologist Role

  • Perform routine and developmental immunochemistry and molecular laboratory techniques.
  • Analyze and evaluate assays for sensitivity and specificity.
  • Embed and prepare sections for various procedures by cutting frozen or paraffin-embedded tissue.
  • Transport tissue specimens to the laboratory.
  • Perform immunohistochemical and in-situ hybridization procedures, including handling and storing probes and antibodies.
  • Mount, label, and distribute prepared microscope slides.
  • Prepare reagent buffers, solutions, and stains.
  • Replace reagents and perform daily maintenance on automated instrumentation.
  • File surgical and autopsy blocks used for immunohistochemical techniques.

Requirements & Tech Stack

  • Histology Technician:
  • American Society for Clinical Pathology (ASCP) Certification eligible in the field of Histology.
  • One year of experience (preferred).
  • Histotechnologist:
  • Bachelor’s Degree in Biology, Microbiology, Chemistry, or a related field, or meet the CLIA qualifications for Histotechnologist (HTL).
  • Histotechnician (HT) or Histotechnologist (HTL) certification or certification eligible by the American Society for Clinical Pathology (ASCP).
  • Working knowledge of OSHA requirements concerning chemical hygiene and bloodborne pathogens.
  • Hands-on laboratory experience from an accredited Histotechnology school or one year of prior histology laboratory experience (preferred).

Qualifications

  • Requires manual dexterity and visual acuity when handling specimens, slides, and utilizing instrumentation.
  • Ability to safely handle potentially infectious patient specimens, carcinogenic substances, odorous, and other hazardous materials.
  • Ability to sit, stand, or walk extensively.
  • Follows standard precautions using personal protective equipment as required.

Pay Range

  • Minimum hourly: $34.00
  • Maximum hourly: $45.65

H-1B sponsor

Cleveland Clinic filed 15 entry-level H-1B applications for new hires (Oct 2025 - Jun 2026, Department of Labor). It may be cap-exempt (no lottery); ask the employer.

See their H-1B record →

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