Research Tech Entry, Lab of Mudit Tyagi
Jefferson Health
About the Role
A highly motivated Research Technician is sought to join a laboratory investigating the molecular and cellular mechanisms underlying HIV persistence, neuroinflammation, accelerated aging, and neurodegeneration. The laboratory utilizes cutting-edge human induced pluripotent stem cell (iPSC)-derived microglia, cerebral organoids, and advanced genomic approaches to identify novel therapeutic targets and develop innovative interventions for HIV-associated and age-related neurological disorders.
Job Description
The successful candidate will participate in multidisciplinary projects focused on understanding how HIV infection, chronic inflammation, and drugs of abuse alter brain function and contribute to neurocognitive impairment, neurovascular dysfunction, and accelerated aging.
Candidates with experience in human iPSC-derived microglia, brain organoids, neuroinflammation, HIV biology, single-cell genomics are particularly encouraged to apply.
Key Responsibilities
- Maintain and expand iPSC cultures
- Assist with generation and maintenance of cerebral organoids
- Perform molecular and cellular biology experiments
- Train new lab staff regarding lab techniques
- Maintain routine lab functions
- Assist with data collection and laboratory organization
- Maintain detailed laboratory records
Requirements & Tech Stack
- Familiarity with molecular biology techniques
Qualifications
- B.S. or M.S. degree in Biology, Neuroscience, Biochemistry, Biomedical Sciences, or a related field
- Experience with mammalian cell culture preferred
- Strong organizational and record-keeping skills
- Ability to work effectively in a multidisciplinary environment