Research Associate I

About the Role

The Allen Institute accelerates science for a healthier world through large-scale research. The Research Associate I – Brain Proteome Organization will join a research team focused on understanding how the proteome of neuronal populations and their synapses shapes brain circuit function. This position offers the opportunity to contribute to the development of next-generation experimental workflows and large-scale datasets in a team-oriented research environment.

Key Responsibilities

• Perform tissue dissections and biochemical preparation of mouse brain samples for downstream molecular profiling and imaging workflows.
• Execute experimental workflows for synapse isolation, fluorescence-based sorting, and proteomic sample preparation.
• Execute histology, fluorescence imaging, and tissue processing workflows.
• Support molecular biology and viral vector preparation workflows.
• Maintain accurate laboratory documentation and experimental records using established methods.
• Contribute to optimization, troubleshooting, and quality control of experimental workflows.
• Coordinate with internal teams and core facilities to support large-scale data and sample generation.
• Present results and summarize experimental progress within the team.
• Follow SOPs, good laboratory practices, and regulatory requirements.

Requirements & Tech Stack

• Bachelor’s degree in neuroscience, biology, biochemistry, molecular biology, chemistry or related field.
• Experience in one or more of the following: molecular biology or biochemistry, mass spectrometry-based proteomics, mouse tissue processing and histology, microscopy, flow cytometry, automation of experimental workflows, or related experimental disciplines.
• Ability to work independently and within a collaborative, multi-disciplinary environment.
• Excellent organizational and communication skills.
• Positive attitude, self-starter, demonstrated attention to detail, and enthusiasm for learning new experimental approaches.

Work Environment

• Exposure to and handling of laboratory animals.
• Laboratory environment - possible chemical, biological, or other hazardous substances exposure.
• Possible exposure to BioSafety Level 2 organisms, such as recombinant viruses.

Physical Demands

• Occasional lifting up to 30 pounds.
• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment.
• Stooping, bending, crouching.

Position Type/Expected Hours of Work

• Occasional evening and weekend hours required.
• This role is currently working onsite and is expected to work onsite for the majority of working hours.
• Primary work location: 615 Westlake Ave N., with flexibility for limited remote work.

Travel

• Occasional travel to partner sites for compliance oversight required.
• Occasional attendance and participation in national and international conferences may be required.

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments

• This opportunity does not sponsor work visas.
• This opportunity does not offer relocation funding.

Annualized Salary Range

• $54,250 - $66,450*
• Final salary depends on required education, experience, level of skills relevant to the role, and work location.

Benefits

• Eligibility for medical, dental, vision, and basic life insurance.
• Eligibility to enroll in the 401k plan.
• Paid time off available.
• Details available at: https://alleninstitute.org/careers/benefits .