Associate Scientist, Upstream MSAT

About the Role

Sanofi's Global MSAT (Manufacturing Sciences, Analytics, and Technology) acts as a crucial link between R&D and Manufacturing, enhancing the current portfolio and delivering future launches of high-quality, innovative drugs and vaccines. Global MSAT is at the forefront of innovation and process excellence in Manufacturing, guiding new products from launch to commercial success, and embracing Data Sciences and Digitalization. This Associate Scientist position is part of the Upstream team within the Recombinant Drug Substance (DS) function of Global MSAT, located at the Mammalian Platform hub in Framingham, MA. The Recombinant DS function owns the Life Cycle Management (LCM) of DS processes.

Key Responsibilities

• Work collaboratively within the Upstream group to execute and participate in the design of bench scale experiments.
• Present data and results within department and project teams.
• Author internal procedures and technical reports.
• Contribute to project teams for technology transfer to pilot scale or commercial manufacturing.
• Set-up and maintain upstream laboratory equipment, systems, and training.
• Design and conduct experiments, interpret data, and present results to department and project teams.
• Analyze process development and commercial manufacturing data to improve process robustness, build process understanding, and develop next-generation processes for monoclonal antibodies and recombinant proteins.
• Contribute to technical investigations of complex deviations in manufacturing.
• Contribute to establishing best practices and technical ways of working within development and manufacturing teams.
• Collaborate with other scientists/engineers across the biologics manufacturing network and with partnership organizations.

Requirements & Tech Stack

• Bachelor's degree in chemical engineering, Biology, Biochemistry, or a similar or related field.
• 0 to 5 years of hands-on experience in laboratory, pilot, or manufacturing scale for biologics products.
• Relevant academic experience (university projects, thesis work, or research) is valued.
• Hands-on experience with cell culture, ideally in mammalian systems.
• Experience in one or more areas of upstream process development: process transfer, scale-up/scale-down, validation, or continuous process verification as applied to mammalian-expressed proteins.
• Experience with statistical analysis software.
• Scientific background, technical writing, and presentation skills.
• Highly motivated, with excellent attention to detail and the ability to work independently and in cross-functional, cross-site teams.
• Flexible with ability to adjust to a fast-paced, goal-oriented environment and willingness to expand and broaden skills.
• Experience in one or more areas applied to cell culture, e.g., medium development, PAT, cell banking, process intensification, computational modelling for biological systems, or lab equipment automation.