Associate Scientist

About the Role

Seeking a highly motivated Sr. Associate to join the Protein Therapeutics (PT) – Protein Chemistry team. PT is a multidisciplinary team with broad capabilities in protein engineering, expression, purification, and characterization. We are responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development.

This role involves supporting the analysis and characterization of large molecule, therapeutic drug candidates, many of which are complex biologics.

Key Responsibilities

• Analyzing and characterizing novel and complex molecules that will be the next generation of large molecule therapeutics.
• Contributing to the execution of our analytics, molecular assessment, and protein purification capabilities.
• Organizing, analyzing, and reporting findings to support lead candidate selection.
• Partnering with Project, Analytics and Automation teams to advance our pipeline.
• Operating and troubleshooting automation platforms for high throughput purification and analytics.
• Performing protein analytics using a variety of techniques and instrumentation.
• Contributing to the development of new processes and methods.
• Capturing experimental data in LIMS/ELN systems.
• Summarizing and reporting results and findings to work group and project teams.

Requirements & Tech Stack

• Protein Purification & Analytics: Experience with techniques, instrumentation, and software.
• Protein Analytical Techniques: HPLC, MCE, etc.
• Analysis Software: Chromeleon, LabChip, etc.
• Communication Skills: Demonstrated strong communication skills.
• Collaboration: Ability to work collaboratively in a cross-functional team environment.
• Automation Platforms: Experience operating and troubleshooting for high throughput purification and analytics.
• Data Management: Experience capturing experimental data in LIMS/ELN systems.
• Chromatography Techniques (Purification Profile): Affinity, IEX, HIC, RP, MMC.
• Liquid Chromatography Instrumentation (Purification Profile): FPLC.
• Chromatography Software (Purification Profile): Unicorn.
• Gel-based protein analysis / running gels.
• Western blot.

Qualifications

• Basic Qualifications:
• Master’s degree in life sciences.
• OR Bachelor’s degree and 2 years of relevant scientific experience.
• Preferred Qualifications:
• Experience with protein purification & analytics, techniques, instrumentation, software.
• Experience with protein analytics, particularly biologic molecules.
• Demonstrated experience with protein analytical techniques (HPLC, MCE, etc…) and analysis software (Chromeleon, LabChip, etc.).
• Knowledge of high throughput purification and analytical techniques is a plus.
• Experience with handling and analyzing large datasets.
• Ability to multi-task, work flexibly and efficiently in a cross-functional environment.
• Demonstrated track record of independent critical thinking and creative problem-solving.
• Experience with protein purification (Purification Profile focus).
• Hands-on protein purification experience within a laboratory environment.
• Relevant protein chemistry and analytical experience is valuable.
• Demonstrated understanding of protein purification processes and the underlying science.