Associate Scientist I, Small Scale Synthesis

About the Role

Arrowhead Pharmaceuticals is seeking an Associate Scientist I to join the Discovery Chemistry department. This role will primarily focus on oligonucleotide synthesis, purification, and analytical chemistry in support of specific program goals. The position contributes to Arrowhead's programs as part of a collaborative team of scientists.

Key Responsibilities

• Perform synthesis, purification, and analysis of oligonucleotides.
• Maintain a well-documented laboratory notebook.
• Track progress against project timelines, generate regular status updates, and communicate progress and issues to management.
• Manage time effectively to meet deadlines.
• Adhere to safe laboratory practices.
• Assist with maintenance of bioconjugate and oligonucleotide inventory.

Requirements & Tech Stack

• B.S. in Chemistry or Biochemistry, with an excellent understanding of organic and analytical chemistry; or equivalent.
• Relevant experience working in a chemistry laboratory.
• Experience with a wide range of analytical techniques, especially HPLC.
• Ability to quickly learn new procedures and techniques.

Preferred Qualifications

• Experience with large-molecule synthetic targets (especially oligonucleotides), in an academic or industry setting.
• Previous experience in a pharmaceutical setting.