Research Associate, Analytical Development

About the Role

Moderna is seeking a Research Associate for a position based at the Norwood, MA site. This individual will contribute to the development, refinement, and implementation of cell-based bioassays supporting release and stability testing for mRNA therapeutics and vaccines. The role requires close partnership with multidisciplinary teams (Quality, Process Development, and Research) to generate scientifically rigorous data for both clinical and commercial programs. This position is site-based and not eligible for remote work.

Key Responsibilities

• Execute cell-based bioassays to evaluate potency and biological activity of mRNA-based medicines.
• Support assay development, optimization, troubleshooting, and qualification activities under guidance.
• Perform routine cell culture and maintain cell lines.
• Analyze and document experimental data with accuracy and attention to detail.
• Assist in identifying sources of assay variability and supporting efforts to enhance assay robustness.
• Follow established protocols, SOPs, and regulatory expectations.
• Contribute to authoring technical documents such as protocols and reports.
• Collaborate with team members and cross-functional partners to support project timelines.

Requirements & Tech Stack

• Hands-on experience with mammalian cell culture, transient transfections, bioassays or related biological techniques.
• Basic data analysis and problem-solving skills.
• Experience maintaining laboratory notebooks and documenting experimental work in a clear and organized manner.
• Strong communicator with a team-oriented mindset.
• Familiarity with GraphPad Prism, data visualization, and basic statistical concepts is a plus.
• Familiarity with techniques such as ELISA, cell-based assays, or reporter assays is a plus.
• Exposure to nucleic acid therapeutics and delivery technologies (e.g., RNA, DNA, LNP, viral vectors) is a plus.

Qualifications

• BS degree in Biochemistry, Molecular Biology, Cell Biology, Immunology, Biological Engineering, or related field.
• Demonstrated scientific curiosity and ability to learn new experimental techniques, troubleshoot challenges, and adapt in a fast-paced research environment.
• Strong attention to detail and ability to follow protocols accurately.

Working Model

• Embraces a 70/30 work model (70% in-office).