Lipid Nanoparticle & mRNA Synthesis Intern

About the Role

As a Research Intern (Lipid Nanoparticle & mRNA Synthesis) at Sartorius, you will contribute to the full product development cycle—from concept to prototype—and collaborate closely with engineers and scientists in a multidisciplinary environment. This is an onsite role based at our Marlborough, MA site, starting October 2026 for six months with a potential extension up to 10 months.

Key Responsibilities

• Conduct systematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.
• Develop and execute protocols for preparing and characterizing nucleic acid–loaded lipid nanoparticle (LNP) formulations using automated LNP synthesis platforms.
• Support LNP process development activities, including screening, scale-up, and manufacturing-relevant workflow optimization.
• Troubleshoot issues with experimental design and execution.
• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

Requirements & Tech Stack

• Hands-on laboratory experience with RNA synthesis, preferably including in vitro transcription.
• Experience with LNP formulation and characterization.
• Familiarity with microfluidic instruments, laboratory automation, 3D printing, advanced cell models, or conjugation reactions is a plus.

Qualifications

• Current graduate student in biomedical, chemical, or mechanical engineering, or a related field with formal education and experience with lipid nanoparticles and/or nucleic acids.
• Experience with characterization techniques such as dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA, or related assays is ideal.
• Strong oral and written communication skills, with the ability to summarize results and present findings clearly.
• Identification with Sartorius' core values: Sustainability, Openness, Enjoyment.

Compensation is up to $30 an hour. No relocation and/or accommodations are offered.