Technical Associate, Annotation and Proofreading

Mindspan Institute

Cambridge, MA0–2 yrs2h agovia LinkedIn

This job at a glance

Who can apply
New grads and up to 2 years
Must know
StatisticsRecruitingExcelPythonData analysis
Work
On-site in Cambridge
Pay
Not stated by the employer.
Skill demand
Excel14%Python8%Statistics5%Recruiting1%of 99 similar entry-level jobs posted in the US this week
Listed
Oct 28, 2026 · still open

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About the Role

This is a hands-on role focused on checking and correcting automated reconstructions. Your annotations will serve as the ground truth for training and measuring models.

Key Responsibilities

  • Annotate and proofread 3D microscopy volumes of brain tissue, including:
  • Tracing neurons.
  • Marking synapses and other structures.
  • Fixing errors from automated segmentation.
  • Write and maintain annotation protocols, including examples of challenging cases.
  • Implement quality control measures, such as reviewing annotations and measuring annotator agreement.
  • Maintain gold-standard datasets for training and verification.
  • Track throughput and error rates, using basic statistics to report on time allocation and quality variations.
  • Provide feedback to tool and model teams regarding annotation bottlenecks and common model errors.
  • Document and systematically analyze problems to develop and refine working protocols.
  • Share protocols and reasoning behind decisions.
  • As the team grows, you will:
  • Train and onboard new annotators.
  • Assign and review annotator work.
  • Assist in recruitment efforts.
  • Potentially lead an annotation team, managing work assignments and tracking quality/throughput.

Requirements & Tech Stack

  • B.S. or B.A. in neuroscience, biology, biomedical engineering, computer science, or a related field, or equivalent experience.
  • Direct hands-on experience with careful visual work on images or data, such as image annotation, histology, microscopy, or data labeling.
  • Ability to apply a written protocol consistently and report deviations.
  • Basic quantitative skills: spreadsheets, simple statistics, and chart interpretation.
  • Excellent attention to detail and scientific rigor.
  • Comfort learning new software and working in 3D image viewers.
  • Strong detail orientation, exceptional organizational, planning, interpersonal, and communication skills.
  • Ability to write clearly, work independently, lead and manage, and prioritize/multitask.
  • Self-motivation, commitment to high quality standards, and a service-oriented mindset.
  • Good judgment, balancing flexibility and focus, action and planning, speed and thoughtfulness.
  • Openness to giving and receiving feedback constructively.
  • This is an in-person job.
  • Flexible hours may be required at times.

Preferred Qualifications

  • Experience with neuron tracing, connectomics proofreading, or volumetric annotation tools (e.g., Neuroglancer, CAVE, webKnossos, VAST, Dragonfly).
  • Knowledge of neuroanatomy or cell biology.
  • Experience training others, writing protocols, and leading a small team.
  • Basic scripting or data analysis (e.g., Python, R).
  • Experience with quality-control methods like inter-rater agreement or gold-standard review.

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