Downstream Process Development Scientist

About the Role

The Eurofins PSS team is seeking a Downstream Scientist to support a client's downstream process development activities for the production of sterile, injectable lentiviral vector (LVV)-based gene therapy products. This role contributes to purification process definition and optimization, process robustness studies, and process transfers.

Key Responsibilities

• Support the execution of purification development and characterization experiments.
• Collaborate with cross-functional teams to coordinate analytical testing, exchange materials, share technical observations, and align on project timelines.
• Support transfer of purification processes to pilot plant and manufacturing sites.
• Maintain lab stocks, supplies, and equipment specific to the downstream team to support daily operations.
• Document process data in electronic lab notebook and shared databases.
• Communicate key observations in team meetings.

Requirements & Tech Stack

• Hands-on experience following established downstream chromatography and filtration protocols, including ion exchange and affinity chromatography, TFF, and/or UF/DF methods.
• Cytiva AKTA liquid chromatography equipment (AKTA pure, AKTA avant) is preferred.
• Experience with statistical design of experiments (DOE) software is preferred.
• Experience with viral vectors is a plus.

Qualifications

Basic Minimum Qualifications:

• B.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 1 year of relevant industry experience.

OR

• M.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 6 months of relevant industry experience.

Additional Qualifications:

• Pragmatic problem solver with a get-it-done attitude.
• Experience documenting process results in electronic lab notebooks.
• Effectively communicate experimental observations to management and cross-functional teams.
• Meticulous attention to detail in sample tracking, experiment execution, data recording, and laboratory documentation.
• Ability to set priorities and multi-task activities to effectively manage workflows and drive deliverables to completion.
• Strong team orientation, with excellent organizational skills, self-motivation, and a positive attitude.
• Strong communication skills, with the ability to clearly communicate experimental results and observations.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Preferred Qualifications:

• Hands-on experience with end-to-end biologics purification process development, MSAT, or manufacturing.

Work Schedule & Location

• This is a full-time, permanent position.
• Monday-Friday, 8am-5pm with periodic work outside of working hours.
• Candidates currently located within commutable distance to Boston, MA are encouraged to apply.

Compensation

• $32.00-$36.00 per hour based on education and relatable industry experience.