Scientist, Pathology

About the Role

Amgen is seeking a Scientist to join the Pathology Laboratory within the Translational Safety & Risk Sciences (TSRS) Department. This role focuses on developing and applying tissue-based assays to support various research and development activities.

Key Responsibilities

• Develop, optimize, validate, and standardize histopathology assays using FFPE samples, including single-plex and multiplex immunohistochemistry (IHC) and in situ hybridization (ISH) in colorimetric and immunofluorescent formats.
• Utilize imaging modalities and digital pathology tools to generate, analyze, and interpret tissue-based data for target qualification, pharmacodynamic and efficacy assessments, and biomarker development.
• Collaborate with pathologists, research investigators, and translational teams to deliver high-quality data supporting mechanism-of-action studies, in vivo model development, and toxicity assessments across therapeutic areas.
• Maintain clear, complete documentation and communicate results through laboratory information systems, databases, and team presentations.

Requirements & Tech Stack

• Doctorate degree OR Master’s degree and 2+ years of relevant research and industry experience OR Bachelor’s degree and 4 years of relevant research and industry experience.
• Demonstrated expertise in pathology-based methods, including IHC, multiplex IHC, ISH, and immunofluorescence imaging.
• Experience analyzing pathology imaging data, including H&E, IHC, multiplex immunofluorescence, and/or spatial transcriptomics.
• Familiarity with whole-slide imaging and digital pathology platforms, such as HALO or Visiopharm, is preferred.
• Experience with automated staining platforms, such as Ventana, Leica Bond, or IntelliPATH, is preferred.
• Ability to manage multiple projects and priorities simultaneously.
• Excellent written and verbal communication skills.
• Strong communication, organizational, and collaboration skills in multidisciplinary scientific environments.

Qualifications

• PhD or master’s degree in cell biology, molecular biology, or related discipline.
• Two or more years of molecular pathology experience, preferably in an industry setting.
• Understanding of machine-learning methods for image segmentation, classification, detection, and representation learning.

What Amgen Offers

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.