Process Development Intern

About the Role

• This is a temporary role with a third-party agency partner.
• The Process Development Intern position is for a 6-month experiential training program.
• Program Dates: January – July 2027.
• Compensation: $30.00 – 50.00 USD/hour.
• Perks: Flexible hours, stock or equity, bonus eligibility.

Key Responsibilities

• Support product development, manufacturing, and laboratory research.
• Contribute to a high-impact cryopreservation process development project for Type 1 Diabetes (T1D) drug product.
• Establish a standardized cryo-microscopy workflow for real-time imaging of stem cell-derived islets during CPA loading, unloading, and controlled freeze/thaw cycles.
• Design and execute cryopreservation studies using selected CPA formulations and loading/unloading strategies.
• Develop an initial computational modeling framework to complement experimental cryo-microscopy data, modeling the correlation between CPA diffusion kinetics, islet size and morphology, and cryopreservation process parameters.
• Integrate experimental and computational results to characterize CPA diffusion kinetics and islet response.
• Use findings to identify promising CPA formulations and loading/unloading strategies and guide next steps for screening and cryopreservation process optimization.

Requirements & Tech Stack

• Currently pursuing a graduate degree (PhD and master’s are preferred) or undergraduate degree in:
• Cell Biology
• Molecular Biology
• Biochemistry
• Biotechnology
• Biomedical Engineering
• Bioengineering
• Chemical or Biochemical Engineering
• Pharmaceutical Sciences
• Computational Biology
• Or a related scientific discipline.
• Mammalian cell culture experience (aseptic technique, routine cell culture handling, media preparation, sample preparation).
• Cell microscopy experience (sample preparation, cell staining, image acquisition, image-based evaluation).
• Foundational knowledge of cell cryopreservation and hands-on experience with cell freezing and thawing.
• Knowledge of and/or experience with computational modeling approaches relevant to molecular dynamics, diffusion kinetics, or cryopreservation processes.
• Strong analytical, problem-solving, and organizational skills.
• Ability to independently troubleshoot experimental challenges.
• Ability to manage priorities and maintain accurate documentation.
• Highly motivated and collaborative team player with strong communication skills.
• Intellectual curiosity and a desire to learn new techniques.

Qualifications

• Experience with stem cells or stem cell-derived products is preferred.
• Experience with cell aggregates, spheroids, organoids, or other three-dimensional cell systems is a plus.
• Experience with cryo-microscopy is a plus.
• You must be enrolled in an advanced degree program if graduating before June 2027.
• Legal authorization to work in the United States.