EPA Volatile Compound Dosimetry for Inhalation

About the Role

This research opportunity is with the U.S. Environmental Protection Agency (EPA), Office of Chemical Safety and Pollution Prevention (OCSPP), located in Research Triangle Park, North Carolina. The project focuses on integrating exposure engineering, analytical chemistry, cell biology, and computational modeling to characterize volatile chemical delivery and cellular uptake across dynamic Air-Liquid Interface (ALI) systems. The goal is to provide experimentally verified dosimetry to improve inhalation New Approach Methodologies (NAMs).

Key Responsibilities

• Develop and apply quantitative methods for characterizing volatile chemical exposure, delivery, and cellular uptake.
• Design, plan, and execute sampling strategies for volatile chemicals in biological and exposure-related matrices.
• Develop and apply analytical approaches (e.g., chromatography, mass spectrometry) for the detection and quantification of volatile chemicals in unknown samples.
• Participate in the planning, setup, and implementation of in vitro inhalation exposure studies.
• Evaluate and interpret analytical data to support exposure characterization and toxicological research.
• Maintain appropriate laboratory records, quality assurance documentation, and data management practices.
• Communicate research findings through reports, presentations, and scientific publications.

Requirements & Tech Stack

• Laboratory experience in analytical chemistry or a related field outside of college courses.
• Knowledge of sample preparation, calibration curve generation, and quality control metrics.
• Experience with analytical instrumentation including gas chromatography and mass analyzers.
• Proficiency performing chemistry calculations.
• Statistical skills related to data analysis and data comparison.
• Familiarity with laboratory quality assurance and quality control (QA/QC) practices.
• Strong written, oral, organizational, and interpersonal communication skills.

Qualifications

• Received or currently pursuing a bachelor's or master's degree in one of the relevant fields: chemistry, analytical chemistry, environmental chemistry, biochemistry, or a closely related discipline.
• Degree must have been received within the past five years.
• Candidates who have obtained a bachelor's degree in one of the relevant fields and have research experience equivalent to a Master's will also be considered.
• Citizenship: U.S. Citizen Only.

Additional Notes

• Anticipated Appointment Start Date: Fall/Winter 2026/2027.
• Appointment Length: Initially one year, renewable for three to four additional years.
• Stipend: $52,693.00 – $64,453.00 Yearly.
• Proof of health insurance is required.
• A successful background investigation by the Office of Personnel Management (OPM) is required.