Associate Scientist/Scientist
Excelsior Sciences
New York, NYFresher2h agovia LinkedIn
This job at a glance
- Who can apply
- New grads, no experience needed
- Must know
- Lean / Six SigmaTroubleshootingStakeholder management
- Nice to have
- Machine learning
- Work
- On-site in New York
- Pay
- $80K–$140K a year
- Skill demand
- Troubleshooting40%Stakeholder management10%Machine learning10%Lean / Six Sigma1%of 99 similar entry-level jobs posted in the US this week
- Listed
- Nov 12, 2026 · still open
Sign in free to see which of these skills your resume already shows.
About the Role
Excelsior Sciences is seeking a synthetic organic chemist to contribute to reinventing small-molecule discovery and manufacturing through Blocc chemistry. The company is building a lean, high-leverage organization at the intersection of chemistry, automation, software, and AI.
Key Responsibilities
- Collaborate with cross-functional teams (automation engineers, analytical, biology, and AI/ML) to drive solutions for automated synthesis of small molecules.
- Develop, troubleshoot, and optimize synthetic routes for rapid generation of complex building blocks.
- Develop and optimize organic reactions, work-up, and SPE purification for automation in a high-throughput screening (HTS) fashion.
- Optimize and test conditions for cleaning synthesized compounds on solid phase support, including metal scavenging.
- Develop LC conditions for final product purification.
- Assist in designing and testing protocols for automation system validations.
- Support continuous automated synthesis of small molecules in an HTS fashion.
- Identify and design synthetic routes for complex building blocks.
- Guide, troubleshoot, and oversee CROs on compound synthesis.
- Support analytical chemists on chromatographic methods development and analytical equipment troubleshooting.
- Establish and maintain synthetic chemistry project timelines.
- Coordinate and drive activities with functional leads.
- Communicate project status and issues to management and stakeholders through meetings and documents.
Qualifications
- PhD degree in Organic Chemistry OR MS in Organic Chemistry with 3+ years of relevant industrial experience.
- Strong background in synthetic organic chemistry.
- Demonstrated ability for taking initiative, creativity, and innovation in problem solving.
- Attention to detail and proactive with excellent follow-through.
- Ability to work both independently and collaboratively with analytical, automation, and biology teams.
- Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.
- Ability to consistently generate quality data.
Requirements & Tech Stack
- Proficient in purification by column chromatography (manual and automated, such as Biotage or equivalent).
- Well versed in analytical technology such as UPLC-MS, NMR, LC-MS, KF.
- Metal-catalyzed organic reactions experience is desired.
- High throughput screening (HTS) expertise is a plus.
- Medicinal chemistry and/or process development experience are an asset.
- Semi-prep or SFC knowledge is a plus.
- Automation and AI/ML knowledge is a plus.
Salary range: $80,000-$140,000 per year.
Benefits package includes health insurance and paid time off.