Engineer (0-3 years)

About the Role

We are seeking an Engineer to join our Formulation Sciences team focused on lipid nanoparticle (LNP) discovery and development for CRISPR-based gene editing therapies. The successful candidate will be responsible for supporting LNP process development, scale-up, and characterization, working as part of a multidisciplinary, fast-paced team environment. The ideal candidate will have some process development industry experience with a desire to contribute to a team focused on championing nanomedicinal products and developing manufacturing solutions based on strong scientific principles.

Key Responsibilities

• Support the design, manufacturing, and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
• Support the design and execution of a wide range of experiments, including DoEs, to advance LNP technology and process development.
• Participate in defining equipment specification/selection, draft procedures, and recommended operating parameters/ranges.
• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports.
• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory.
• Multi-task across several projects and manage time effectively to achieve results.
• Collaborate with multiple cross-functional teams and execute other duties as assigned.

Requirements & Tech Stack

• Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field.
• Experience with lipid nanoparticle formulations and analytical characterization methods (Preferred).
• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing (preferred).
• Proficiency in literature search and relevant computer software skills.

Qualifications

• Strong problem-solving skills, and a creative/innovative approach in problem solving.
• Ability to work independently and in very dynamic, interdisciplinary team environments.
• Proven record in working with partners/collaborators (desirable).
• Organized, detail-oriented, and an innovative self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills.
• Minimum of 2 years of relevant industry experience.