Research Associate, In Vivo

About the Role

E11 Bio is seeking a Research Associate to run the in vivo work that produces every sample the platform depends on. This role is open to early-career applicants as well as experienced technicians, with level and compensation set by experience.

Key Responsibilities

• Execute retro-orbital and stereotaxic viral injections, with post-operative monitoring.
• Prepare perfusates and run perfusions to SOP standards, and keep perfusion and surgical setups operational.
• Collect and process tissue, including sectioning of the fixed brain, histology and immunostaining, and imaging.
• Run colony management and animal supply: breeding, weaning, genotyping workflows, health checks, and record keeping.
• Support perfusion development: run controlled perturbations and document QC outcomes.
• Prepare equipment and supplies for experiments, keep reagents and consumables stocked, and flag supply problems early.
• Work to approved animal protocols and comply with federal and institutional IACUC regulations.
• Keep accurate, reproducible experimental records.

Requirements & Tech Stack

• STEM field (BS/BA or MS degree)
• Experience with rodent handling, restraint, and procedures under an approved protocol.
• Willingness to work with small animals and animal tissue.
• Strong lab notebook practice, careful experimental documentation, and attention to detail.
• Ability to work some weekends as needed, with days off swapped for weekdays.

Preferred Qualifications

• Hands-on experience performing animal perfusions with PFA or related fixatives.
• Experience with stereotaxic or retro-orbital viral injections.
• Experience with transgenic mouse colony management, including breeding and genotyping workflows.
• Experience with histology, brain excision or sectioning, and with acquiring images on a fluorescence microscope.

Additional Notes

• This role is with Convergent Research at E11 Bio in Alameda, California.
• The team is described as collaborative, interdisciplinary, and operating like a nimble, tight-knit start-up.
• Motivated by moonshot neuroscience and working on a high-impact project.
• Committed to open science.

Compensation

• Base salary range: $74,000 - $125,000 a year.
• Bonus: Performance-based, up to 20% of base salary.
• Total potential compensation: $93,000 - $157,500.
• 401K matching up to 6% of base salary.
• Stipend for fitness and wellness activities.